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phenomaster feeding chambers  (TSE systems)


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    TSE systems phenomaster feeding chambers
    Figure 1. Fmr1 knockout (KO) male mice are heavier than controls. (a) Litter sizes were normalized to 8 mice per litter, weight of 4 litters per genotype monitored from p7-p90, and Fmr1 KO mice compared to wild- type FVB controls (WT) (KO, red; WT controls, black; males, top; females, bottom). n = 12–16 mice, points represent group mean ± standard error. Statistical significance between weight at each age is represented with * (p < 0.05, ANOVA followed by Tukey’s post hoc test). (b) Food (left) and water (right) intake were not different (cumulative, n = 8 per genotype); glucose levels (random, left; measured after overnight fasting, right) were not different (WT, black bars represent group mean ± standard error, each black circle represents one animal; KO, red bars represent group mean ± standard error, each red square represents one animal). (c) Locomotion activity of male mice measured continuously with <t>Phenomaster</t> for 48 h. Left, x-axis indicates time of day, when monitoring started at 14:00 or 2 pm, shaded area represents dark cycle, lights off in our vivarium from 7 pm to 7 am; black line, WT; red line, Fmr1 KO; n = 8 mice, points represent group mean ± standard error; WT, black; KO, red. Right, area under the curve (AUC), WT, black bars represent group mean ± standard error, each black circle represents one animal; KO, red bars represent group mean ± standard error, each red square represents one animal. (d) Locomotion activity, female mice. Statistical significance (*, p < 0.05) was determined with t-test followed by Tukey’s post hoc test.
    Phenomaster Feeding Chambers, supplied by TSE systems, used in various techniques. Bioz Stars score: 96/100, based on 902 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/phenomaster+feeding+chambers/PhenoMaster/pm37542065-66-16-19
    Average 96 stars, based on 902 article reviews
    phenomaster feeding chambers - by Bioz Stars, 2026-09
    96/100 stars

    Images

    1) Product Images from "Increased body weight in mice with fragile X messenger ribonucleoprotein 1 (Fmr1) gene mutation is associated with hypothalamic dysfunction."

    Article Title: Increased body weight in mice with fragile X messenger ribonucleoprotein 1 (Fmr1) gene mutation is associated with hypothalamic dysfunction.

    Journal: Scientific reports

    doi: 10.1038/s41598-023-39643-z

    Figure 1. Fmr1 knockout (KO) male mice are heavier than controls. (a) Litter sizes were normalized to 8 mice per litter, weight of 4 litters per genotype monitored from p7-p90, and Fmr1 KO mice compared to wild- type FVB controls (WT) (KO, red; WT controls, black; males, top; females, bottom). n = 12–16 mice, points represent group mean ± standard error. Statistical significance between weight at each age is represented with * (p < 0.05, ANOVA followed by Tukey’s post hoc test). (b) Food (left) and water (right) intake were not different (cumulative, n = 8 per genotype); glucose levels (random, left; measured after overnight fasting, right) were not different (WT, black bars represent group mean ± standard error, each black circle represents one animal; KO, red bars represent group mean ± standard error, each red square represents one animal). (c) Locomotion activity of male mice measured continuously with Phenomaster for 48 h. Left, x-axis indicates time of day, when monitoring started at 14:00 or 2 pm, shaded area represents dark cycle, lights off in our vivarium from 7 pm to 7 am; black line, WT; red line, Fmr1 KO; n = 8 mice, points represent group mean ± standard error; WT, black; KO, red. Right, area under the curve (AUC), WT, black bars represent group mean ± standard error, each black circle represents one animal; KO, red bars represent group mean ± standard error, each red square represents one animal. (d) Locomotion activity, female mice. Statistical significance (*, p < 0.05) was determined with t-test followed by Tukey’s post hoc test.
    Figure Legend Snippet: Figure 1. Fmr1 knockout (KO) male mice are heavier than controls. (a) Litter sizes were normalized to 8 mice per litter, weight of 4 litters per genotype monitored from p7-p90, and Fmr1 KO mice compared to wild- type FVB controls (WT) (KO, red; WT controls, black; males, top; females, bottom). n = 12–16 mice, points represent group mean ± standard error. Statistical significance between weight at each age is represented with * (p < 0.05, ANOVA followed by Tukey’s post hoc test). (b) Food (left) and water (right) intake were not different (cumulative, n = 8 per genotype); glucose levels (random, left; measured after overnight fasting, right) were not different (WT, black bars represent group mean ± standard error, each black circle represents one animal; KO, red bars represent group mean ± standard error, each red square represents one animal). (c) Locomotion activity of male mice measured continuously with Phenomaster for 48 h. Left, x-axis indicates time of day, when monitoring started at 14:00 or 2 pm, shaded area represents dark cycle, lights off in our vivarium from 7 pm to 7 am; black line, WT; red line, Fmr1 KO; n = 8 mice, points represent group mean ± standard error; WT, black; KO, red. Right, area under the curve (AUC), WT, black bars represent group mean ± standard error, each black circle represents one animal; KO, red bars represent group mean ± standard error, each red square represents one animal. (d) Locomotion activity, female mice. Statistical significance (*, p < 0.05) was determined with t-test followed by Tukey’s post hoc test.

    Techniques Used: Knock-Out, Activity Assay

    Related Articles

    Activity Assay:

    Article Title: Genetic and Environmental Causes of Obesity and Their Impact on Hypothalamic Function and Pituitary Plasticity
    Article Snippet: .. 2.3.2 Feeding behavior and locomotor activity WT and Fmr1 KO mice between 8-10 weeks of age were individually housed in Phenomaster feeding chambers (TSE Systems, Chesterfield, MO, USA) to analyze food intake and locomotion, and received access to standard chow and water ad libitum throughout behavioral testing. ..



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    TSE systems phenomaster feeding chambers
    Figure 1. Fmr1 knockout (KO) male mice are heavier than controls. (a) Litter sizes were normalized to 8 mice per litter, weight of 4 litters per genotype monitored from p7-p90, and Fmr1 KO mice compared to wild- type FVB controls (WT) (KO, red; WT controls, black; males, top; females, bottom). n = 12–16 mice, points represent group mean ± standard error. Statistical significance between weight at each age is represented with * (p < 0.05, ANOVA followed by Tukey’s post hoc test). (b) Food (left) and water (right) intake were not different (cumulative, n = 8 per genotype); glucose levels (random, left; measured after overnight fasting, right) were not different (WT, black bars represent group mean ± standard error, each black circle represents one animal; KO, red bars represent group mean ± standard error, each red square represents one animal). (c) Locomotion activity of male mice measured continuously with <t>Phenomaster</t> for 48 h. Left, x-axis indicates time of day, when monitoring started at 14:00 or 2 pm, shaded area represents dark cycle, lights off in our vivarium from 7 pm to 7 am; black line, WT; red line, Fmr1 KO; n = 8 mice, points represent group mean ± standard error; WT, black; KO, red. Right, area under the curve (AUC), WT, black bars represent group mean ± standard error, each black circle represents one animal; KO, red bars represent group mean ± standard error, each red square represents one animal. (d) Locomotion activity, female mice. Statistical significance (*, p < 0.05) was determined with t-test followed by Tukey’s post hoc test.
    Phenomaster Feeding Chambers, supplied by TSE systems, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/phenomaster+feeding+chambers/PhenoMaster/pm37542065-66-16-19
    Average 96 stars, based on 1 article reviews
    phenomaster feeding chambers - by Bioz Stars, 2026-09
    96/100 stars
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    Figure 1. Fmr1 knockout (KO) male mice are heavier than controls. (a) Litter sizes were normalized to 8 mice per litter, weight of 4 litters per genotype monitored from p7-p90, and Fmr1 KO mice compared to wild- type FVB controls (WT) (KO, red; WT controls, black; males, top; females, bottom). n = 12–16 mice, points represent group mean ± standard error. Statistical significance between weight at each age is represented with * (p < 0.05, ANOVA followed by Tukey’s post hoc test). (b) Food (left) and water (right) intake were not different (cumulative, n = 8 per genotype); glucose levels (random, left; measured after overnight fasting, right) were not different (WT, black bars represent group mean ± standard error, each black circle represents one animal; KO, red bars represent group mean ± standard error, each red square represents one animal). (c) Locomotion activity of male mice measured continuously with Phenomaster for 48 h. Left, x-axis indicates time of day, when monitoring started at 14:00 or 2 pm, shaded area represents dark cycle, lights off in our vivarium from 7 pm to 7 am; black line, WT; red line, Fmr1 KO; n = 8 mice, points represent group mean ± standard error; WT, black; KO, red. Right, area under the curve (AUC), WT, black bars represent group mean ± standard error, each black circle represents one animal; KO, red bars represent group mean ± standard error, each red square represents one animal. (d) Locomotion activity, female mice. Statistical significance (*, p < 0.05) was determined with t-test followed by Tukey’s post hoc test.

    Journal: Scientific reports

    Article Title: Increased body weight in mice with fragile X messenger ribonucleoprotein 1 (Fmr1) gene mutation is associated with hypothalamic dysfunction.

    doi: 10.1038/s41598-023-39643-z

    Figure Lengend Snippet: Figure 1. Fmr1 knockout (KO) male mice are heavier than controls. (a) Litter sizes were normalized to 8 mice per litter, weight of 4 litters per genotype monitored from p7-p90, and Fmr1 KO mice compared to wild- type FVB controls (WT) (KO, red; WT controls, black; males, top; females, bottom). n = 12–16 mice, points represent group mean ± standard error. Statistical significance between weight at each age is represented with * (p < 0.05, ANOVA followed by Tukey’s post hoc test). (b) Food (left) and water (right) intake were not different (cumulative, n = 8 per genotype); glucose levels (random, left; measured after overnight fasting, right) were not different (WT, black bars represent group mean ± standard error, each black circle represents one animal; KO, red bars represent group mean ± standard error, each red square represents one animal). (c) Locomotion activity of male mice measured continuously with Phenomaster for 48 h. Left, x-axis indicates time of day, when monitoring started at 14:00 or 2 pm, shaded area represents dark cycle, lights off in our vivarium from 7 pm to 7 am; black line, WT; red line, Fmr1 KO; n = 8 mice, points represent group mean ± standard error; WT, black; KO, red. Right, area under the curve (AUC), WT, black bars represent group mean ± standard error, each black circle represents one animal; KO, red bars represent group mean ± standard error, each red square represents one animal. (d) Locomotion activity, female mice. Statistical significance (*, p < 0.05) was determined with t-test followed by Tukey’s post hoc test.

    Article Snippet: WT and Fmr1 KO mice between 8 and 10 weeks of age were individually housed in Phenomaster feeding chambers (TSE Systems, Chesterfield, MO, USA) to analyze food intake and locomotion, and received access to standard chow and water ad libitum throughout behavioral testing.

    Techniques: Knock-Out, Activity Assay